A comparison of the pharmacology of two potent analgesic agents, piminodine (Win 14,098-2) and Win 13,797, with morphine and meperidine*1, *2
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چکیده
منابع مشابه
A comparison of the pharmacology of two potent analgesic agents, piminodine (Win 14,098-2) and Win 13,797, with morphine and meperidine.
When meperidine (Demerol) was shown to possess marked analgesic properties (Eisleb and Schaumann, 1939) and thus became the first potent synthetic analgesic drug, the importance of the 1,4-substituted piperidine nucleus in providing analgesic activity became apparent. Many modifications of this basic chemical structure have been synthesized and studied pharmacologically in an attempt to achieve...
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ژورنال
عنوان ژورنال: Toxicology and Applied Pharmacology
سال: 1961
ISSN: 0041-008X
DOI: 10.1016/0041-008x(61)90072-2